Hypermethylation of DLG3 Promoter Upregulates RAC1 and Activates the PI3K/AKT Signaling Pathway to Promote Breast Cancer Progression

Figure 1

Downregulation of DLG3 and hypermethylation of its promoter region in breast cancer. (a) Measurement of DLG3 expression in breast cancer (BC) and paracancerous (normal) tissues by qRT-PCR; (b) evaluation of DLG3 protein expression in BC and normal tissues by western blot; (c) determination of DLG3 expression in BC cells and MCF10A by qRT-PCR; (d) bisulfite sequencing PCR results of methylation levels of DLG3 in BC and normal tissues; and (e) bisulfite sequencing PCR results of methylation levels of DLG3 in BC cells and MCF 10A. ; .

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