Research Article

Effects of Chengqi Decoction on Complications and Prognosis of Patients with Pneumonia-Derived Sepsis: Retrospective Cohort Study

Table 1

Patient characteristics at baseline.

TotalChengqi decoctionControlP

Patients (n)282141141
Male (n (%))162 (100)75 (46.29)87 (53.70)0.223
Age (years)67.00 (67.00–87.25)67.00 (48.00–87.00)67.00 (55.00–90.00)0.484
BMI (kg/m2)23.66 (21.25–25.39)24.22 (22.04–30.48)23.31 (20.29–25.39)0.006
APACHE II score24.30 ± 7.2025.23 ± 6.3323.40 ± 8.000.222
SOFA score12.00 (11.00–15.00)13.00 (11.00–15.00)12.00 (10.00–14.00)0.189
HR (bpm)94.00 (78.00–113.25)88.00 (60.00–102.00)97.00 (89.00–115.00)0.010
SBP (mmHg)115.00 (105.00–127.50)115.00 (105.00–126.00)111.00 (98.00–129.00)0.803
DBP (mmHg)49.50 (45.00–62.25)50.00 (44.00–63.00)49.00 (45.00–61.00)0.771
MAP (mmHg)72.00 (63.00–85.50)72.00 (62.00–83.00)72.00 (65.00–88.00)0.688
CVP (mmHg)8.95 ± 5.138.62 ± 5.528.28 ± 4.610.204
WBC12.56 (4.19–23.90)4.37 (3.72–23.90)14.19 (7.19–23.90)0.065
NG%81.20 (80.10–87.68)81.20 (79.10–87.30)81.20 (80.10–89.90)0.655
CRP (mg/L)73.00 (45.75–85.00)73.00 (34.00–89.00)74.00 (54.00–84.00)0.303
Procalcitonin (ng/mL)5.11 (2.50–12.30)3.12 (1.60–7.30)8.10 (4.50–23.90)≤0.001
PH7.39 (7.30–7.44)7.38 (7.29–7.43)7.39 (7.30–7.46)0.137
PaO2102.00 (91.00–126.00)102.00 (91.00–126.00)108.00 (90.40–126.00)0.955
PaCO246.90 (44.00–60.40)45.80 (41.50–59.10)46.90 (44.50–61.00)0.101
PaO2/FiO2232.77 ± 64.61217.58 ± 63.68247.95 ± 62.140.021
Lactate (mmol/L)1.95 (1.30–3.30)1.79 (1.30–2.60)2.10 (1.30–4.00)0.246
ScvO264.31 ± 13.8159.86 ± 13.7968.69 ± 12.350.002
NT-proBNP (pg/mL)5348.50 (2201.00–12180.00)2392.00 (1569.00–7810.00)7899.00 (3883.00–15015.00)≤0.001
SCr (µmol/L)184.39 (97.16–280.80)113.39 (95.34–280.00)188.00 (154.90–308.00)0.106
BUN (mmol/L)13.19 (8.80–16.41)10.50 (7.58–15.20)15.61 (12.00–19.66)≤0.001

SOFA, sequential organ failure assessment; BMI, body mass index; APACHE, Acute Physiology and Chronic Health Evaluation; BUN, blood urea nitrogen; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial blood pressure; CVP, central venous pressure; WBC, white blood cell; NG%, neutrophilic granulocyte percentage; CRP, C-reactive protein; PaO2, arterial partial pressure of oxygen; PaCO2, arterial partial pressure of carbon dioxide; PaO2/FiO2, arterial partial pressure of oxygen/inspired oxygen fraction; ScvO2, central (mixed) venous oxygen saturation; NT-proBNP, N-terminal B-type natriuretic peptide; SCr, serum creatinine.