Effects of Chengqi Decoction on Complications and Prognosis of Patients with Pneumonia-Derived Sepsis: Retrospective Cohort Study

Table 3

Univariate and multivariate models for overall survival on day 28.

Covariate at study entry	HR	95% CI	P
Univariate models
NT-proBNP (pg/mL) (<1800 vs. ≥1800)	0.31	0.09–1.00	0.05
BMI (kg/m^2) (18–23 vs. >23 or <18)	1.51	0.76–3.02	0.24
Age (years) (≤65 vs. >65)	1.70	0.84–3.41	0.14
Gastrointestinal bleeding (present vs. absent)	0.67	0.23–1.90	0.44
Abdominal distension (present vs. absent)	0.73	0.36–1.46	0.37
APACHE II score (<25 vs. ≥25)	2.12	0.98–4.59	0.06
FiO2/PaO2 (<150 vs. ≥150)	0.04	0.01–13.60	0.29
Lactate (mmol/L) (<2 vs. ≥2)	0.65	0.32–1.31	0.23
ScvO2 (%) (<75 vs. ≥75)	0.85	0.40–1.85	0.69
Group (Chengqi decoction vs. control)	0.48	0.23–0.97	0.04
Multivariate models
Group (Chengqi decoction vs. control)	0.48	0.23–0.97	0.04
APACHE II score (<25 vs. ≥25)	2.02	0.89–4.60	0.09
NT-proBNP (pg/mL) (<1800 vs. ≥1800)	0.34	0.09–1.19	0.09
Age (≤65 years vs. >65 years)	1.39	0.67–2.88	0.38

Adjusted for: NT-proBNP, age, APACHE II score. HR, hazard ratio; NT-proBNP, N-terminal B-type natriuretic peptide; BMI, body mass index; FiO₂/PaO₂, inspired oxygen fraction/arterial partial pressure of oxygen; ScvO₂, central venous oxygen saturation; APACHE, Acute Physiology and Chronic Health Evaluation.