Study on the Mechanism of Reducing Hepatotoxicity of Water-Grinding Realgar by Metabolomics, Morphology, and Chemical Analysis

Figure 4

PCA and OPLS-DA plots with different groups. Scores plots of principal components analysis and orthogonal partial least squares discriminant analysis models with the statistical parameters as follows: (a) R2X = 0.622, Q2 = 0.389; (b) R2X = 0.620, Q2 = 0.472; (c) R2X = 0.577, Q2 = 0.389; (d) R2X = 0.554, Q2 = 0.365; (e) R2X = 0.761, Q2 = 0.894; (f) R2X = 0.660, Q2 = 0.870; (g) R2X = 0.750, Q2 = 0.667; (h) R2X = 0.785, Q2 = 0.532; (i) R2X = 0.420, Q2 = 0.889; (j) R2X = 0.717, Q2 = 0.917; (k) R2X = 0.853, Q2 = 0.887; (l) R2X = 0.548, Q2 = 0.369. QC, quality control group; Group C, control group; Group HG-r, high-dose grinding-realgar group; Group HWG-r, high-dose water-grinding-realgar group; Group CC, convalescent control group; Group CHG-r, high-dose grinding-realgar convalescent group; Group CHWG-r, high-dose water-grinding-realgar convalescent group.

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