Idebenone-Activating Autophagic Degradation of <i>α</i>-Synuclein via Inhibition of AKT-mTOR Pathway in a SH-SY5Y-A53T Model of Parkinson’s Disease: A Network Pharmacological Approach

<div>Enrichment analysis of potential targets of Idebenone for Parkinson’s disease. (a) Top 20 Gene Ontology biological processes. (b) Top 20 Gene Ontology cellular components. (c) Top 20 Gene Ontology molecular functions. (d) Top 20 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. The size of the bubble represents the number of targets in the pathway and the color represents the <i>q</i> value. The red represents a smaller <i>q</i> value.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 2: Idebenone-Activating Autophagic Degradation of <i>α</i>-Synuclein via Inhibition of AKT-mTOR Pathway in a SH-SY5Y-A53T Model of Parkinson’s Disease: A Network Pharmacological Approach 

Figure 2 | Idebenone-Activating Autophagic Degradation of α-Synuclein via Inhibition of AKT-mTOR Pathway in a SH-SY5Y-A53T Model of Parkinson’s Disease: A Network Pharmacological Approach 