Research Article

Idebenone-Activating Autophagic Degradation of α-Synuclein via Inhibition of AKT-mTOR Pathway in a SH-SY5Y-A53T Model of Parkinson’s Disease: A Network Pharmacological Approach

Table 1

The autodocking details of Idebenone binding to AKT1, AKT2, and MAPK1.

DrugTargetsPDB IDBinding energy (kcal·mol−1)

IdebenoneAKT14gv1−5.23
AKT23d0e−4.67
MAPK14n0s−5.14