EGCG Promotes Neurite Outgrowth through the Integrin β1/FAK/p38 Signaling Pathway after Subarachnoid Hemorrhage

Figure 1

EGCG inhibited superoxide anion generation after SAH. (a) Superoxide anion fluorescence distribution in cells detected by fluorescence microscopy. Normal cells showed less fluorescence (A). OxyHb at a final concentration of 10 μM significantly increased fluorescence intensity (B). EGCG, added 30 min before the addition of OxyHb, significantly reduced superoxide anion level almost to basal level (C). Similar trend of superoxide anion level was also observed in NAC group, which was added 30 min after the addition of OxyHb (D). Bar, 200 μm. (b) Quantification of superoxide anion fluorescence intensity. The values represent three independent experiments. vs. control, vs. control, and vs. SAH.

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