Unfermented Freeze-Dried Leaf Extract of Tongkat Ali (Eurycoma longifolia Jack.) Induced Cytotoxicity and Apoptosis in MDA-MB-231 and MCF-7 Breast Cancer Cell Lines

Figure 16

Representative flow cytometric scan of untreated MCF-7 cells and those treated with unfermented freeze-dried leaf extract of E. longifolia at IC₅₀ value for 24 h, 48 h and 72 h. (a) p53, (b) Bax and (c) Bcl-2 expressions. Blue peak = unstained cells. The purple peak at 0 h = Untreated cells. The purple peak at 24, 48 and 72 h = Treated cells with extract at the respective treatment period.

(a)

(b)

(c)