Antimalarial Effect of the Root of Silene macrosolen A. Rich (Caryophyllaceae) on Plasmodium-berghei-Infected Mice

Table 6

Effect of the crude extract of S. macrosolen on body weight and rectal temperature of P. berghei-infected mice in the prophylactic test.

Groups	Weight (g)			Temperature
	D4	D7	% changes	D4	D7	% changes
DW10 ml/kg	28.27 ± 0.49	24.33 ± 0.30	−13.89	35.97 ± 0.16	33.07 ± 0.23	−8.06
CQ25	29.28 ± 0.72	28.52 ± 0.72	−2.52^a2	36.23 ± 0.08	35.70 ± 0.18	−1.47^a2
SM100	27.63 ± 0.80	24.80 ± 0.67	−10.22^b2	36.15 ± 0.19	33.58 ± 0.15	−7.10^b2
SM200	29.27 ± 1.06	26.23 ± 0.78	−10.24^b2	36.37 ± 013	34.13 ± 0.33	−6.14^b2
SM400	27.85 ± 0.71	25.78 ± 0.57	−7.35^a2b1	36.48 ± 0.14	34.37 ± 0.28	−5.80^b2

Data are expressed as mean ± SEM (n = 6); CQ = chloroquine; DW = distilled water; SM = Silene macrosolen; D4 = day 4; D7 = day7; a = compared to the negative control; b = compared to the positive control; 1 = ; 2 = .