Research Article
Derrone Inhibits Platelet Aggregation, Granule Secretion, Thromboxane A2 Generation, and Clot Retraction: An In Vitro Study
Figure 4
Inhibitory action of derrone on TXA2 generation and cPLA2 and p38MAPK phosphorylation. (a) Inhibitory action of derrone on collagen-induced TXA2 generation. (b) Inhibitory action of derrone on collagen-induced cPLA2 (Ser505) phosphorylation. (c) Inhibitory action of derrone on collagen-induced p38MAPK phosphorylation. Measurement of TXA2 generation and western blotting was performed as described in the Materials and Methods section. Data are expressed as mean ± standard deviation (n = 4). and versus the collagen-stimulated human platelets.
(a) |
(b) |
(c) |