Cortisol Secretion and Subsequent Impaired Lymphopoiesis after Starvation Can Be Reduced by Moxibustion Treatment

Figure 1

Experimental design. (a) The representation of Mox treatment (CV12) and lymphoid organ (thymus, spleen, and bone marrow). (b) The time course of changes in cell number and cellularity of lymphoid organs during starvation; a nonstarved group was sacrificed on day 0, whereas four starved groups were sacrificed at 2, 4, 6, or 8 d following starvation, and lymphopoiesis was subsequently analyzed. (c) The effects of Mox treatment; five Mox-treated groups were treated 1, 2, 3, 4, or 5 times. These five groups and the sham-treated groups were then starved 1 d following the final treatment. Lymphopoiesis was analyzed on day 2 or 4, when the decline in cell number was most prominent. (d) Changes in bodyweight during and following Mox treatment and starvation (n = 8). The nonstarved mice group is marked with empty circles, whereas the starved mice group is marked with black triangles (sham-treated) and gray quadrangles (Mox-treated).

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