Metabolomics and Network Pharmacology-Based Investigation into the Mechanisms Underlying the Therapeutic Effect of a New Chinese Traditional Medicine (Cui Nai Ling) on Bromocriptine-Induced Hypogalactia

Table 4

The value for the most significant 20 nodes in the PPI network between NCNL and lactation.

Node value	Proteins
102	Insulin (INS)
98	Albumin (ALB)
90	Interleukin 6 (IL6)
84	Caspase 3 (CASP3)
80	Epidermal growth factor receptor (EGFR)
79	Vascular endothelial growth factor A (VEGFA)
78	MYC proto-oncogene (MYC)
76	Mitogen-activated protein kinase 8 (MAPK8)
65	Estrogen receptor 1 (ESR1)
64	Cyclin D1 (CCND1)
60	Cytochrome c (CYCS)
60	Fos proto-oncogene (FOS)
59	Peroxisome proliferator-activated receptor gamma (PPARG)
52	Androgen receptor (AR)
52	Erb-b2 receptor tyrosine kinase 2 (ERBB2)
51	RELA proto-oncogene (RELA)
48	Catenin beta-1 (CTNNB1)
46	Caspase 8 (CASP8)
45	MDM2 proto-oncogene (MDM2)
44	Apolipoprotein B (APOB)

Node value: the higher the degree value, the closer the interaction.