Evaluation of Beneficial and Adverse Effects of a Diet Supplemented with Schisandrae Fructus Seed Ethanol Extract on Lipid and Glucose Metabolism in Normal and Hypercholesterolemic/Hyperglycemic Mice

Figure 3

Effect of dietary supplementation with EtSF-S or FF on serum, hepatic, and fecal lipids in ND- and HFFD-fed mice. Mice were fed with normal diet (ND) or high fructose/fat diet (HFFD) for 3 months. Then, animals were fed with ND or HFFD without and with supplementation with the ethanol extract of Schisandrae Fructus (SF) seed (EtSF-S) or fenofibrate (FF). After 30 days of experiment, serum and hepatic total cholesterol (TC) and triacylglycerol (TG) levels including fecal TC contents were measured. The concentrations of EtSF-S in chow diet were estimated on the basis of crude herbal material (SF seed). Values given are the mean ± SD, with N = 10. , vs. ND alone; ^†, ^†† vs. HFFD alone.

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