Study on the Potential Mechanism of Fructus Tribuli in the Treatment of Hypertensive Vascular Remodeling Based on Network Pharmacology and Molecular Docking

Table 1

Detailed information on 17 active compounds from FT.

Number	Molecule ID	Molecule name	Molecule weight	OB (%)	DL
FT1	MOL000354	Isorhamnetin	316.28	49.60	0.31
FT2	MOL000359	Sitosterol	414.79	36.91	0.75
FT3	MOL000422	Kaempferol	286.25	41.88	0.24
FT4	MOL000483	(Z)-3-(4-hydroxy-3-methoxy-phenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide	313.38	118.35	0.26
FT5	MOL008559	(2aR,2’R,4R,6aR,6bS,8aS,8bR,11aS,12aR,12bR)-4-((S)-2-(2,6-dimethylphenyl)propoxy)-5’,5’,6a,8a-tetramethyl-8-methylenedocosahydro-1H-spiro[pentaleno[2,1-a]phenanthrene-10,2’-pyran]	573.00	59.49	0.28
FT6	MOL008563	(3R,8S,9S,10R,13R,14R,17S)-17-((2S,5R)-5-ethyl-6-methylheptan-2-yl)-3-hydroxy-10,13-dimethyl-3,4,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-7(2H)-one	428.77	40.93	0.79
FT7	MOL008567	(3R,7R,8S,9S,10S,13R,14S,17R)-17-((2R,5S)-5-ethyl-6-methylheptan-2-yl)-3,10-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-7-ol	414.79	34.21	0.76
FT8	MOL008568	(Z)-3-(3,4-dihydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide	299.35	113.25	0.24
FT9	MOL008569	β-sitosterol-β-D-glucopyranoside	398.79	32.41	0.71
FT10	MOL008588	Terrestriamide	327.36	114.09	0.29
FT11	MOL008590	(2aR,2’S,4R,4’R,5’S,6aS,6bS,8aS,8bR,9S,11aR,12aR,12bR)-4,4’-dihydroxy-5’,6a,8a,9-tetramethylicosahydro-1H-spiro[pentaleno[2,1-a]phenanthrene-10,2’-pyran]-8(2H)-one	444.72	58.74	0.76
FT12	MOL008593	(2aR,5S,6aS,6bS,8aS,8bS,11aS,12aR,12bR)-10-isopentyl-6a,8a,9-trimethyl-2,2a,3,4,5,6,6a,6b,7,8,8a,8b,11a,12,12a,12b-hexadecahydro-1H-naphtho[2',1':4,5]indeno[2,1-b]furan-5-ol	400.71	39.21	0.84
FT13	MOL007291	Hecogenin	430.69	15.86	0.79
FT14	MOL008581	Tigogenin	416.71	13.83	0.81
FT15	78177919	Terrestrosin D	1049.16	—	—
FT16	122169314	Terrestrosin K	1079.18	—	—
FT17	—	Terrestroside B	1312.63	—	—