Research Article

Gas Chromatography-Mass Spectrometry Coupled with Multivariate Statistical Analysis to Identify the Alpha Glucosidase Inhibitors from Flesh of Salacca zalacca Fruits and Their Molecular Docking Studies

Table 1

Extraction yield and α-glucosidase inhibitory activity of S. zalacca fruit extracts.

Extracts (ethanol/water)Percentage yield (%)α-Glucosidase inhibitory activity IC50 (µg/mL)

0% (E0)69.4 ± 3.6b,c280. 30 ± 20.34a
20% (E20)67.2 ± 2.4c150.90 ± 14.32b
40% (E40)67.7 ± 2.1c182 ± 19.32c
60% (E60)72.6 ± 2.7a,b16.48 ± 1.20d,e
80% (E80)75.5 ± 2.2a25.09 ± 1.54d
100% (E100)20.2 ± 1.4d20.08 ± 1.24d,e
Quercetinnd3.54 ± 0.32e

Values represent the mean ± standard deviation (n = 6). The values that do not share a letter are significantly different at . nd = not determined.