Cichoric Acid Ameliorates Monosodium Urate-Induced Inflammatory Response by Reducing NLRP3 Inflammasome Activation via Inhibition of NF-kB Signaling Pathway

Figure 2

Effect of CA on the mRNA levels of iNOS and CD86 in the THP-M cells. The expression levels of iNOS and CD86 were detected by RT-PCR. The mRNA levels of iNOS and CD86 were normalized to MUS (a). Inhibitory effects of CA on IL-1β and TNF-α secretion in the THP-M cells. The culture medium was collected, and the levels of IL-1β and TNF-α were determined by ELISA (b). The results are presented as mean ± SD (n = 3). , vs. the MUS group.

(a)

(b)