The Neuroprotective Effect of Byu d Mar 25 in LPS-Induced Alzheimer's Disease Mice Model

Figure 1

Testing of spatial learning and memory in AD + NS, AD + donepezil, and AD + BM25 groups by Morris water maze. (a) The swimming trajectory of mice in the AD + NS, AD + donepezil, and AD + BM25 groups. (b) Escape latency in AD + NS, AD + donepezil, and AD + BM25 groups. (c) Probe trial; the travel trajectory of mice in the AD + NS, AD + donepezil, and AD + BM25 groups. (d) The frequency of crossing the target platform in AD + NS, AD + donepezil, and AD + BM25 groups. A significant difference in escape latency in the AD+BM25 group rather than that in the AD+NS group was detected (). A more significant frequency in crossing the target platform in AD+BM25 groups than that in the AD+NS group was detected (). Data are expressed as the mean ± standard error of the mean (SEM). (n = 8/group in the AD + BM25 group; n = 8/group in the AD + donepezil group; n = 8/group in the AD + NS group). BM25: Byu d Mar 25; AD: Alzheimer’s disease; NS: normal saline.