Chemical Composition, Protective Effects, and Mechanisms of Volatile Oil from Fructus Gleditsiae Abnormalis with Nasal Administration against Ischemic Injury in HFD and MCAO-Induced Rats
Table 2
Effects of VOFGA on neuroethology and cerebral edema (n = 5).
Groups
Dose (mg/kg)
Behavioral score
Brain water content (%)
Normal
—
0
70.61 ± 1.12
Sham
—
0
70.01 ± 1.27
Model
—
3.00 ± 0.00
86.09 ± 0.76
Nimodipine
5.0
0.20 ± 0.44##
72.74 ± 1.46##
VOFGA
0.0
3.00 ± 0.00
85.30 ± 1.89
VOFGA
0.077
2.00 ± 0.70##
79.59 ± 1.03##
VOFGA
0.154
1.00 ± 0.70##
75.23 ± 1.03##
VOFGA
0.308
0.40 ± 0.54##
72.43 ± 1.28##
Compared with the normal group, ,. Compared with the model group, ,.