Aconitine Induces TRPV2-Mediated Ca²⁺ Influx through the p38 MAPK Signal and Promotes Cardiomyocyte Apoptosis

Figure 2

The effect of aconitine on p38 MAPK signaling and TRPV2 expression. (a) The expressions of p38 and p-p38 in each group. (b) The level of TRPV2 mRNA was measured by qRT-PCR. (c) The expressions of total TRPV2 and membrane TRPV2. NC: negative control; t-TRPV2: total TRPV2; m-TRPV2: membrane TRPV2.  < 0.05,  < 0.001, and  < 0.0001 vs. the NC group.

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