Potential Interaction of Fresh Garlic with Metformin during Ischemia-Reperfusion Induced Cardiac Injury in Diabetic Rats
Table 1
Effect on body weight and blood sugar.
Groups
Body weight (g)
Blood glucose (mg/dl)
Baseline
At the end of four weeks
At the end of eight weeks
Baseline
At the end of eight weeks
72 hours after alloxan
Diabetic control
202.71 ± 6.2
218.32 ± 9.2
245.52 ± 8.2c
160 ± 1.7
193.23 ± 3.5b
329.28 ± 3.1c
D-GH
210.98 ± 8.3
224.41 ± 10.3
252.54 ± 11.1c
148 ± 2.4
185.67 ± 7.7b
312.56 ± 7.5c
D-MET
204.73 ± 10.5
222.21 ± 8.8
258.32 ± 9.7c
110 ± 1.5
153.23 ± 6.9b
321.56 ± 8.5c
D-(GH + MET)
210.45 ± 8.2
226.82 ± 7.2
260.43 ± 8.3c
122 ± 1.8
185.39 ± 8.5b
316.54 ± 10.6c
Data are given as mean ± SEM, where b and c when compared to baseline; D-GH, GH of 250 mg/kg in diabetic rats; D-MET, MET of 70 mg/kg in diabetic rats; and D-(GH + MET), GH plus MET in diabetic rats.