Synergistic Regulation of Microglia Gene Expression by Natural Molecules in Herbal Medicine

Figure 4

GO functional classification on DEGs. GO terms are divided into three ontologies: biological process, molecular function, and cellular component. (a–c) The GO functional classification of Ala group, Deh group, and Mix group. (d–f) The top 20 enriched GO terms of those groups. The X-axis indicated the number of genes in a category. All groups were involved in GO_BP including immune system process (GO:0002376), innate immune response (GO:0045087), and inflammatory response (GO:0006954) and GO_MF including protein binding (GO:0005515), nucleotide binding (GO:0000166), and identical protein binding (GO:0042802), respectively. (a) Ala vs LPS, (b) Deh vs LPS, and (c) Mix vs LPS.

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