Yiqi Huoxue Recipe Regulates Autophagy through Degradation of Advanced Glycation End Products via mTOR/S6K1/LC3 Pathway in Diabetic Nephropathy

Table 2

Biochemical indicators of rats in each group ( ± s, n = 8).

Group	Blood glucose (mmol/L)	Glycated hemoglobin (%)	Urine protein (mg/L)	Urine microprotein (ug/mL)	Creatinine (umol/L)	Urea nitrogen (mmol/L)	TG (mmol/L)	LDL (mmol/L)	HDL (mmol/L)
Normal group	6.78 ± 0.57	4.66 ± 0.61	279.49 ± 28.96	17.82 ± 1.80	141.55 ± 15.31	317.58 ± 28.37	0.61 ± 0.09	0.27 ± 0.04	2.75 ± 0.28
Diabetic group	30.63 ± 1.94	24.86 ± 2.26	806.46 ± 68.78	25.69 ± 2.26	31.17 ± 4.26	193.17 ± 19.40	1.38 ± 0.14	1.05 ± 0.10	3.78 ± 0.39
Blood glucose fluctuation group	31.41 ± 1.85	25.77 ± 2.09	832.47 ± 76.51	25.72 ± 2.89	31.30 ± 3.41	183.93 ± 19.05	1.53 ± 0.15	1.04 ± 0.12	3.83 ± 0.40
Benazepril hydrochloride group	19.33 ± 1.53^☆☆##	13.63 ± 1.37^☆☆##	450.02 ± 41.88^☆☆##	18.15 ± 1.91^☆☆##	81.32 ± 8.35^☆☆##	274.13 ± 23.83^☆☆##	1.24 ± 0.13^##	0.48 ± 0.06^☆☆##	2.82 ± 0.29^☆☆##
YHR low-dose group	28.59 ± 1.72^☆##	22.40 ± 1.90^☆##	674.48 ± 68.27^☆☆##	21.45 ± 2.01^☆☆##	115.97 ± 13.05^☆☆##	206.38 ± 21.49^#	1.43 ± 0.17	1.08 ± 0.10	3.45 ± 0.34
YHR middle-dose group	23.41 ± 1.86^☆☆##	18.11 ± 1.81^☆☆##	585.84 ± 53.60^☆☆##	20.00 ± 1.77^☆☆##	94.83 ± 10.42^☆☆##	216.45 ± 21.73^★##	1.21 ± 0.19^☆##	0.62 ± 0.05^☆☆##	3.29 ± 0.32^★##
YHR high-dose group	20.90 ± 1.56^☆☆##	15.30 ± 1.43^☆☆##	446.32 ± 49.28^☆☆##	18.44 ± 1.90^☆☆##	88.82 ± 8.66^☆☆##	226.31 ± 21.05^☆☆##	1.10 ± 0.12^☆☆##	0.52 ± 0.06^☆☆##	2.87 ± 0.29^☆☆##

YHR: Yiqi Huoxue recipe; TG: triglyceride; LDL: low-density lipoprotein; HDL: high-density lipoprotein. Compared with the normal group, , . Compared with the diabetic group, ^☆, ^☆☆. Compared with the blood glucose fluctuation group, ^#, ^##.