Research Article

Yiqi Huoxue Recipe Regulates Autophagy through Degradation of Advanced Glycation End Products via mTOR/S6K1/LC3 Pathway in Diabetic Nephropathy

Table 3

The contents of AGEs in blood and kidney tissues of rats (‾χ ± s, n = 8).

GroupSerum-AGEs (ng/ml)Tissue-AGEs (ng/ml)

Normal group0.64 ± 0.060.68 ± 0.06
Diabetic group0.93 ± 0.100.93 ± 0.08
Blood glucose fluctuation group0.95 ± 0.081.01 ± 0.10
Benazepril hydrochloride group0.66 ± 0.08☆☆##0.73 ± 0.09☆☆##
YHR low-dose group0.82 ± 0.08☆##0.85 ± 0.07☆##
YHR middle-dose group0.81 ± 0.06☆##0.78 ± 0.09☆☆##
YHR high-dose group0.69 ± 0.08☆☆##0.74 ± 0.06☆☆##

YHR: Yiqi Huoxue recipe; AGEs: advanced glycation end products. Compared with the normal group, , . Compared with the diabetic group, , ☆☆. Compared with the blood glucose fluctuation group, #, ##.