Research Article

Yiqi Huoxue Recipe Regulates Autophagy through Degradation of Advanced Glycation End Products via mTOR/S6K1/LC3 Pathway in Diabetic Nephropathy

Table 4

HE semiquantitative scale of rats (‾χ ± s, n = 6).

GroupSemiquantitative scoring

Normal group
Diabetic group2.83 ± 0.41
Blood glucose fluctuation group2.67 ± 0.52
Benazepril hydrochloride group1.17 ± 0.75☆☆##
YHR low-dose group1.83 ± 0.75☆#
YHR middle-dose group1.67 ± 0.82☆#
YHR high-dose group1.50 ± 0.55☆☆##

YHR: Yiqi Huoxue recipe. 0: normal; 1: the glomerular basement membrane thickened slightly and the mesangial membrane proliferated slightly; 2: the renal capsule was significantly enlarged, the renal tubules were focal degeneration, the glomerular basement membrane was obviously thickened, and the mesangial membrane was hyperplasia; 3: the glomerular basement membrane was thickened and the mesangial membrane was hyperplasia. Compared with the diabetic group, , ☆☆. Compared with blood glucose fluctuation group, #, ##.