Yiqi Huoxue Recipe Regulates Autophagy through Degradation of Advanced Glycation End Products via mTOR/S6K1/LC3 Pathway in Diabetic Nephropathy
Table 5
The mTOR, S6K1, and LC3 II expression in the kidney tissues detected by qRT-PCR (‾χ ± s, n = 3).
Group
mTOR
S6K1
LC3 II
Normal group
1.00 ± 0.11
1.00 ± 0.11
1.00 ± 0.10
Diabetic group
4.83 ± 0.53
3.59 ± 0.41
0.43 ± 0.06
Blood glucose fluctuation group
5.02 ± 0.62
3.89 ± 0.46
0.47 ± 0.07
Benazepril hydrochloride group
2.64 ± 0.27☆☆##
2.07 ± 0.21☆☆##
0.65 ± 0.07☆#
YHR low-dose group
3.66 ± 0.40☆#
2.70 ± 0.29☆#
0.87 ± 0.09☆☆##
YHR middle-dose group
3.27 ± 0.36☆#
2.52 ± 0.27☆#
0.73 ± 0.08☆☆#
YHR high-dose group
2.86 ± 0.30☆☆##
2.20 ± 0.39☆☆##
0.72 ± 0.08☆☆#
YHR: Yiqi Huoxue recipe. Compared with the normal group, ∗P < 0.05, ∗∗P < 0.01. Compared with the diabetic group, ☆,☆☆. Compared with the blood glucose fluctuation group, #,##.
