Exploring the Mechanism of Berberine Intervention in Ulcerative Colitis from the Perspective of Inflammation and Immunity Based on Systemic Pharmacology

Figure 3

(a) Effect of berberine on serum IL-1, TNF-α, and IL-4 levels. (b) Effect of berberine on serum IL-6, IL-8, IL-10, and IL-12/P70 levels. (c) IL-1, TNF-α, and IL-4 in colon tissue (immunohistochemistry, x200). (d) Expressions of IL-1, TNF-α, and IL-4 in colon tissue (^∗compared with normal control group,  < 0.05; ^#compared with model group,  < 0.05; A: normal group; B: model group; and C: berberine group).

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