Research Article
Acute and Subchronic Toxicological Evaluation of the Herbal Product HAD-B1 in Rats
Table 8
Histopathological findings of rats for 4-week recovery.
| | Organ | N | Histological findings | Male | Female | | G1 | G4 | G1 | G4 |
| | Liver | 5 | Inflammatory cell foci | | Minimal, multifocal | 0 | 0 | 1 | 0 | | Kidney | 5 | Tubular basophilia | | Minimal, multifocal | 1 | 1 | 0 | 0 | | Medullary cyst | | Present | 0 | 1 | 0 | 0 | | Adrenal gland | 5 | Cortical vacuolation | | Slight, diffuse | 0 | 1 | 0 | 0 | | Heart | 5 | Inflammatory cell infiltration | | Minimal, multifocal | 1 | 0 | 0 | 0 | | Lung | 5 | Alveolar macrophage infiltration | | Minimal, multifocal | 1 | 0 | 0 | 0 |
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