Combination of Chinese and Western Medicine Optimizes the Intestinal Microbiota of Exacerbated Chronic Obstructive Pulmonary Disease in Rats

Figure 1

Evaluation of the efficacy of the intervention of combination Chinese and western medicine in AECOPD rats. (a) FVC. (b) FEV_0.3. (c) FEV_0.3/FVC. (d) CRP in serum. (e) SAA in serum. The data are expressed as means ± SD, n = 5, one-way ANOVA. , compared to control group; , compared to COPD group; , compared to AECOPD group. (f)∼(j) Pulmonary tissue pathology stained with HE (100x). (f) Control group, the pulmonary alveoli are complete. (g) COPD group, the structure of the alveoli is incomplete, and some of the alveoli walls are fractured and fused. (h) AECOPD group, the alveoli are badly damaged, and there are large numbers of bubble wall broken and confluent. (i) MXF/STL group, the alveoli structure has been repaired. (j) TMS/FS group, the alveoli structure was repaired to complete. (k)∼(o) Intestinal tissue pathology stained with HE (200x). (k) Control group, there are few inflammatory cells between the intestinal mucous membrane layer and the muscle layer. (l) COPD group, inflammatory cells can be found. (m) AECOPD group, there are large numbers of inflammatory cells and red blood cell immersion. (n) MXF/STL group, some inflammatory cells and red blood can be seen. (o) TMS/FS group, inflammatory cells and red blood cells are almost invisible.

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