Research Article

New Therapeutic Insight into the Effect of Ma Huang Tang on Blood Pressure and Renal Dysfunction in the L-NAME-Induced Hypertension

Table 2

Effect of MHT on the body weight, water intake, urine volume, and osmolality in urine of L-NAME-induced hypertension rats.

Cont.L-NAMEOMT 10 (mg/kg/day)MHT 50 (mg/kg/day)MHT 100 (mg/kg/day)

Water intake (ml/day)22.4 ± 1.320.9 ± 4.425.3 ± 3.918.06 ± 9.423.7 ± 5.0
Urine volume (g/23 h)32.9 ± 1.042.4 ± 5.932.9 ± 2.532.2 ± 0.435.7 ± 2.2
Osmolality (mOsm/kg H2O)2262.7 ± 110795 ± 79.91932.6 ± 82.3###1510.5 ± 19.5##1720.8 ± 94.6###
Albumin (g/dl)0.473 ± 0.010.60 ± 0.050.56 ± 0.060.433 ± 0.07#0.269 ± 0.02###

Water intake and urine samples were acquired for 1 day at last week of experiment. Cont.: control; MHT: Ma Huang Tang; and OMT: Olmetec. The data of values shows mean ±  S.E.(n = 4 per group). ; versus control; #, ##, and ### versus L-NAME.