HIF-1α RNAi Combined with Asparagus Polysaccharide Exerts an Antiangiogenesis Effect on Hepatocellular Carcinoma In Vitro and In Vivo

Figure 3

Effect of HIF-1α RNAi combined with ASP on the expression of MAPK and PI3K signaling pathway-related proteins. (a) Relative expression of HIF-1α and VEGF mRNA analyzed using qPCR. and versus control group. , , and versus LV-shHIF1α + ASP group. (b)-(c) Protein levels of HIF-1α, VEGF, AKT, p-AKT, ERK, and p-ERK assessed using western blot. , , and versus control group. , , and versus LV-shHIF1α + ASP group.

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