HIF-1α RNAi Combined with Asparagus Polysaccharide Exerts an Antiangiogenesis Effect on Hepatocellular Carcinoma In Vitro and In Vivo

Figure 4

Effect of HIF-1α RNAi combined with ASP on HCC growth and angiogenesis in a SK-Hep1 xenograft nude mouse model. (a)-(b), (d) Tumor volume and weight. , , and versus LV-shHIF1α + ASP group. (c), (e) Protein levels of HIF-1α, VEGF, AKT, p-AKT, ERK, and p-ERK assessed using western blot. , , and versus control group. , , and versus LV-shHIF1α + ASP group.

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