Fisetin Attenuates Arsenic-Induced Hepatic Damage by Improving Biochemical, Inflammatory, Apoptotic, and Histological Profile: In Vivo and In Silico Approach
Table 1
Presents the outcomes of biochemical analysis along with total protein content.
Groups
Control
Arsenic
Arsenic + Fisetin
Fisetin
CAT (U/mg protein)
7.62 ± 0.09a
3.58 ± 0.26b
6.77 ± 0.06a
6.99 ± 0.07a
SOD (U/mg tissue)
6.34 ± 0.12a
3.29 ± 0.09b
5.65 ± 0.06a
6.19 ± 0.11a
GSR (nm NADPH oxidized/min/mg tissue
3.03 ± 0.06a
1.62 ± 0.16b
2.66 ± 0.06a
2.96 ± 0.05a
GSH (nM/min/mg protein)
15.87 ± 0.21a
8.99 ± 0.121b
14.98 ± 0.07a
15.17 ± 0.09a
ROS (U/mg tissue)
TBARS (nM/min/mg tissue)
14.47 ± 0.2a
22.750 ± 0.27b
15.91 ± 0.07a
15.16 ± 0.19a
Total protein (µg/mg tissues)
4.04 ± 0.08a
1.88 ± 0.06b
3.85 ± 0.04a
4.02 ± 0.07a
Superscripts indicate considerable difference at probability value < 0.05.