Research Article

Fisetin Attenuates Arsenic-Induced Hepatic Damage by Improving Biochemical, Inflammatory, Apoptotic, and Histological Profile: In Vivo and In Silico Approach

Table 1

Presents the outcomes of biochemical analysis along with total protein content.

GroupsControlArsenicArsenic + FisetinFisetin

CAT (U/mg protein)7.62 ± 0.09a3.58 ± 0.26b6.77 ± 0.06a6.99 ± 0.07a
SOD (U/mg tissue)6.34 ± 0.12a3.29 ± 0.09b5.65 ± 0.06a6.19 ± 0.11a
GSR (nm NADPH oxidized/min/mg tissue3.03 ± 0.06a1.62 ± 0.16b2.66 ± 0.06a2.96 ± 0.05a
GSH (nM/min/mg protein)15.87 ± 0.21a8.99 ± 0.121b14.98 ± 0.07a15.17 ± 0.09a
ROS (U/mg tissue)
TBARS (nM/min/mg tissue)14.47 ± 0.2a22.750 ± 0.27b15.91 ± 0.07a15.16 ± 0.19a
Total protein (µg/mg tissues)4.04 ± 0.08a1.88 ± 0.06b3.85 ± 0.04a4.02 ± 0.07a

Superscripts indicate considerable difference at probability value  < 0.05.