Atractylenolide III Attenuates Apoptosis in H9c2 Cells by Inhibiting Endoplasmic Reticulum Stress through the GRP78/PERK/CHOP Signaling Pathway

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Targets</td><td class="align_center">Vina score</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">GRP78</td><td class="align_center">−7.5</td></tr><tr><td class="align_left">PERK</td><td class="align_center">−8.1</td></tr><tr><td class="align_left">IRE<i>α</i></td><td class="align_center">−7.9</td></tr><tr><td class="align_left">ATF6</td><td class="align_center">−6.4</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Docking of native ligand with GRP78, PERK, IRE<i>α</i>, and ATF6.</div>

Evidence-Based Complementary and Alternative Medicine

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Table 2

Table 2: Atractylenolide III Attenuates Apoptosis in H9c2 Cells by Inhibiting Endoplasmic Reticulum Stress through the GRP78/PERK/CHOP Signaling Pathway 

Table 2 | Atractylenolide III Attenuates Apoptosis in H9c2 Cells by Inhibiting Endoplasmic Reticulum Stress through the GRP78/PERK/CHOP Signaling Pathway 