[Retracted] Ginsenoside Rg1 Suppresses Non-Small-Cell Lung Cancer via MicroRNA-126-PI3K-AKT-mTOR Pathway

Figure 4

miR-126 targets PIK3R2 and PI3K/mTOR signaling in lung cancer cells. (a) The functions of miRNAs are elucidated with analyses of the genes they target. PIK3R2 was identified as a putative target of miR-126; (b) KD of miR-126 could increase the protein level of phospharylated PI3K and mTOR, but not the protein level of total PI3K and mTOR in A549 cells; (c) KD of miR-126 could increase the protein level of phospharylated PI3K and mTOR, but not the protein level of total PI3K and mTOR in H1650 cells.

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