[Retracted] Ginsenoside Rg1 Suppresses Non-Small-Cell Lung Cancer via MicroRNA-126-PI3K-AKT-mTOR Pathway

Figure 6

Blocking PI3K compromised increase of miR-126 KD on apoptosis in lung cancer cells. (a) Two si-PI3KR2 vectors significantly decreased mRNA expression of PI3KR2 in A549 cells (, , n = 4); (b) KD of PI3KR2 compromised increase of miR-126 KD on increase of caspase 3 mRNA expression in A549 cells (, n = 4); (c) KD of PI3KR2 compromised increase of miR-126 KD on increase of caspase 9 mRNA expression in A549 cells (, , n = 4); (d) KD of PI3KR2 compromised increase of miR-126 KD on decrease of cell viability in A549 cells (, , n = 4); (e) two si-PI3KR2 vectors and si-scramble vectors were transfected in H1650 cells, which indicated that two si-PI3KR2 vectors significantly decreased mRNA expression of PI3KR2 in H1650 cells (, , n = 4); (f) KD of PI3KR2 compromised increase of miR-126 KD on increase of caspase 3 mRNA expression in H1650 cells (, , n = 4); (g) KD of PI3KR2 compromised increase of miR-126 KD on increase of caspase 9 mRNA expression in H1650 cells (, n = 4); (h) KD of PI3KR2 compromised increase of miR-126 KD on decrease of cell viability in H1650 cells (, , n = 4).

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)