Research Article

Anti-Biofilm, Antibacterial, and Anti-Quorum Sensing Activities of Selected South African Plants Traditionally Used to Treat Diarrhoea

Table 1

Characteristics of the plant species investigated.

Plant name (family name)Common nameTraditional usePart usedPrevious pharmacological activitiesVoucher number

Searsia pendulina (Jacq.) Moffett (Anacardiaceae)Witkaree (Afrikaans), garas (nama), mosilabele (South Sotho)Stomach ailments, enema in children [10]LeavesCytotoxicity, antioxidant, and antimicrobial activities [11]PRU 127997
Searsia leptodictya (Diels) T. S. Yi, A. J. Mill. & J. Wen (Anacardiaceae)Mountain karee (English), klipkaree (Afrikaans), mohlwehlwe (N. Sotho)Gastrointestinal disorder [12]LeavesCytotoxicity, antioxidant, and antimicrobial activities [11]PRU 70151
Searsia gueinzii (Sond.) F. A Barkley (Anacardiaceae)Thorny karee (English)Gastrointestinal infections [13]RootMutagenicity and antimutagenicity [13]PRE 1004257
Searsia lancea (L.f.) F. A. Barkley (Anacardiaceae)Rooikaree (Afrikaans), mokalabata (N. Sotho), inhlangutshane (Siswati), mosilabele (Thwana and S. Sotho) mushakaladza (Venda)Diarrhoea and gall sickness [14]Bark and leavesAntibacterial, antihelmintic, and cytotoxicity [15]PRU 126859
Searsia batophylla (Codd) Moffett (Anacardiaceae)Bramble currant (English), Braamtaaibos (Afrikaans)///PRE 1004267
Bauhinia galpinii N.E.Br. (Syn Bauhinia galpinii var. ungulata L.) (Fabaceae)Pride of de kaap (English), vlam-van-die-vlakte (Afrikaans)Gastrointestinal disorder, infertility, amenorrhoea, inflammation, and infectious diseases [16]Leaves, bark, and seedAntibacterial, and antioxidant, antimutagenic, cytotoxic activities [17, 18]PRU 28944
Bauhinia bowkeri (Harv.) A. Schmitz (Fabaceae)White Bauhinia (English), Kiebeesklou (Afrikaans), umdlandlovuGastrointestinal infection, induce vomiting, bathing, and steaming [19]Leaves and barkAnti-inflammatory, antibacterial, and antifungal activity [19]PRU 127998
Bauhinia variegata L. (Fabaceae)Mountain ebony, butterfly tree, orchid tree (English)Diarrhoea, dysentery, goitre, diabetes [20]Leaves and barkAnti-inflammatory [21], Immunomodulatory [22]PRU 38533
Brachylaena transvaalensis E. Phillips and Schweick (Asteraceae)Forest silver-oak (English), vaalboom (Afrikaans), mufhata (Venda), iPhahla (Siswati)Diarrhoea [23]Leaves and barkAntimicrobial activity [24]PRU 126858

PRU: H.G.W.J. Schweickerdt Herbarium, University of Pretoria; PRE: Pretoria National Herbarium, South African National Biodiversity Institute, Pretoria; and /: not reported.