Anti-Biofilm, Antibacterial, and Anti-Quorum Sensing Activities of Selected South African Plants Traditionally Used to Treat Diarrhoea

Table 2

Minimum inhibitory concentration (in mg/mL), cytotoxicity, and selectivity index (in brackets) of acetone plant extracts.

Plant	E. coli25922	E. coli35218	E. coli O157: H7	S. enteritidis	B. cereus	P. aeruginosa	S. aureus	E. faecalis	S.Typhimurium	LC50 (mg/mL)
Searsia pendulina	0.08 (0.37)	0.05 (0.56)	0.06 (0.48)	0.06 (0.44)	0.33 (0.09)	0.09 (0.31)	0.06 (0.43)	0.06 (0.45)	0.08 (0.37)	0.03 ± 0.00
Searsia leptodictya	0.08 (1.33)	0.06 (1.62)	0.08 (1.33)	0.08 (1.33)	0.16 (0.67)	0.09 (1.09)	0.07 (1.41)	0.13 (0.80)	0.16 (0.67)	0.11 ± 0.00
Searsia lancea	0.04 (5.82)	0.08 (2.55)	0.09 (2.19)	0.13 (1.53)	0.03 (6.11)	0.04 (4.36)	0.04 (5.09)	0.05 (3.52)	0.06 (3.05)	0.20 ± 0.02
Searsia batophylla	0.11 (1.32)	0.08 (1.90)	0.18 (0.82)	0.08 (1.90)	0.21 (0.63)	0.08 (1.80)	0.08 (1.71)	0.20 (0.73)	0.08 (1.90)	0.15 ± 0.01
Bauhinia galpinii	0.08 (14.48)	0.08 (14.48)	0.08 (14.48)	0.04 (25.18)	0.32 (3.37)	0.20 (4.83)	0.10 (10.86)	0.14 (7.90)	0.13 (8.69)	>1
Bauhinia bowkeri	0.07 (8.46)	0.08 (6.34)	0.09 (5.19)	0.01 (50.75)	0.27 (1.83)	0.10 (4.96)	0.06 (7.61)	0.15 (3.36)	0.06 (7.61)	0.51 ± 0.04
Gentamicin	0.005	0.005	0.001	0.010	0.005	0.002	0.005	0.005	0.002	nd
Doxorubicin	nd									0.01 ± 0.00

nd = not determined, bold values indicate significant SI values, and .