Evaluation of the Safety and Efficacy of Xiao Yao San as a Treatment for Anxiety: A Systematic Review and Meta-Analysis

Table 2

Intervention characteristics.

Study	Interventions of treatment group		Interventions of control group	Days
	XYS	Anxiolytics	Anxiolytics
Chen and Lj [17]	Xiaoyao san decoction, 150 ml Bid	None	Flupentixol and melitracen tablets, 10.5 mg Bid	42
Deng [18]	Xiaoyao san granule, 5 g Bid	Paroxetine, 20–40 mg Qd	Paroxetine, 20–40 mg Qd	28
Ding [19]	Xiaoyao san decoction Bid	Buspirone, 5–10 mg Tid	Buspirone, 5–10 mg Tid	56
Li [20]	Xiaoyao san granule, 8 granule Tid	None	Alprazolam, 0.4–1.2 mg/day	56
Li [20]	Xiaoyao san decoction Bid	Buspirone, 10 mg Tid	Buspirone, 10 mg Tid	42
Li [20]	Xiaoyao san decoction, 200 ml Bid	None	Paroxetine, 20 mg Qd	28
Wang [22]	Xiaoyao san decoction, 150 ml Bid	Doxepin 25 mg tid + alprazolam 0.4–1.2 mg Bid + oryzanol 20 mg Tid	Doxepin 25 mg tid + alprazolam 0.4–1.2 mg bid + oryzanol 20 mg Tid	56
Wang [23]	Xiaoyao san granule, 9 g Tid	Flupentixol and melitracen tablets, 10.5 mg Bid	Flupentixol and melitracen tablets, 10.5 mg Bid	42
Zhu [24]	Xiaoyao san decoction, 150 ml Bid	Buspirone, 10 mg Tid	Buspirone, 10 mg Tid	42