Research Article

[Retracted] High CHAF1A Expression Levels Are Positively-Correlated with PD-L1 Expression and Indicate Poor Prognosis in Gastric Cancer

Table 3

The correlations between the CHAF1A expression levels and the clinicopathological features of gastric cancer patients and the univariate analysis of gastric cancer patients.

VariablesCHAF1A expressionTotalHigh rateχ2-value
HighLow

Age (years)
 ≤ 6056278367.47%3.1400.076
 > 6030275752.63%

Gender
 Male624010260.78%2.2900.089
 Female17213844.74%

Family history (gastric cancer)
 Yes1742180.95%7.8260.005
 No576211947.90%

Smoking history
 Yes35155070%5.8260.016
 No44469048.89%

Drinking history
 Yes16193545.71%0.0870.768
 No456010542.86%

Weight loss
 Yes30235356.60%0.0010.794
 No49388756.32%

Tumor location
 Proximal34134772.34%0.0010.425
 Distal42448648.84%
 Unknown34742.86%

Borrmann type
 I/II46337958.23%0.6790.410
 III/IV33265955.93%
 Unknown0220

Lauren type
 Intestinal41266761.20%1.2320.540
 Mixed1292157.14%
 Diffuse26255150.98%
 Unknown0110

Tumor size (cm)
 > 5 cm52378958.42%0.2570.613
 ≤ 5 cm27235054%
 Unknown0110

Grade of differentiation
 Poor/moderate-poor31326349.21%2.2070.137
 Moderate/well44277161.97%
 Unknown42666.67%

T stage

T1/20880%10.9890.001

T3/4795313259.85%

N stage
 N0/126164261.90%0.7320.392
 N2/353459854.08%

M stage
 M0705712755.12%0.9550.328
 M1941369.23%

TNM stage
 Ι/II8111942.11%1.6350.201
 III/IV715012158.68%

HER-2
 Positive5131827.78%2.0960.148
 Negative566612245.90%

PD-L1
 Positive27214856.25%4.7760.029
 Negative34589236.96%

AFP (ng/ml)
 ≤ 8.1716013154.20%5.6720.017
 > 8.1707100%
 Unknown11250%

CEA (ng/ml)
 ≤ 5525010250.98%4.8700.027
 > 527113871.05%

CA199 (U/ml)
 ≤ 3752449654.17%0.0500.824
 > 3727174461.36%

CA724 (U/ml)
 ≤ 6.941519244.57%0.0510.821
 > 6.915173246.88%
 Unknown5111645.45%

CA125 (U/ml)
 ≤ 35705912954.26%0.3090.578
 > 35741163.64%

CA50 (U/ml)
 ≤ 2533356848.53%0.4590.498
 > 25641960.0%
 Unknown20335337.73%

Statistically significant ().