Ethnopharmacological-Based Validation of Polyalthia suberosa Leaf Extract in Neurological, Hyperalgesic, and Hyperactive Gut Disorders Using Animal Models

Table 2

Effect of Polyalthia suberosa on thiopental sodium-induced sleeping time in mice (mean ± SEM, n = 6).

Group	Dose	Latent period	Sleeping time	% effect
Control (1% v/v Tween-80: water)	10 ml kg^−1	87.33 ± 1.45	136.67 ± 9.53	0.0
Standard (diazepam)	3 mg kg^−1	2.6 ± 0.88	337.8 ± 14.19	96.94
PS-250	250 mg kg^−1	40 ± 7.21	251.67 ± 6.57	51.53
PS-500	500 mg kg^−1	50.66 ± 3.84	273 ± 8.76	41.01

indicates  < 0.05, indicates  < 0.01, and indicates  < 0.001 when compared with control.