Ethnopharmacological-Based Validation of Polyalthia suberosa Leaf Extract in Neurological, Hyperalgesic, and Hyperactive Gut Disorders Using Animal Models
Table 3
Effect of Polyalthia suberosa on the open field test in mice (mean ± SEM, n = 6).
Group
Dose
Number of movements (% of movement inhibition)
0 min
30 min
60 min
90 min
120 min
Control
10 ml kg−1
26.5 ± 0.64
27.75 ± 0.47
28.0 ± 0.63
27.5 ± 0.65
27.5 ± 0.64
Standard
3 mg kg−1
20.5 ± 0.28
13.0 ± 0.41
10.5 ± 0.65
9.25 ± 0.48
8.25 ± 0.48
PS-250
250 mg kg−1
24.0 ± 0.40
18.25 ± 0.47
16.5 ± 0.64
15.55 ± 0.64
15.73 ± 0.85
PS-500
500 mg kg−1
23.25 ± 0.48
16.0 ± 0.41
13.5 ± 0.65
13.25 ± 0.48
13.5 ± 0.64
indicates < 0.05, indicates < 0.01, and indicates < 0.001 when compared with control.
