Ethnopharmacological-Based Validation of Polyalthia suberosa Leaf Extract in Neurological, Hyperalgesic, and Hyperactive Gut Disorders Using Animal Models
Table 4
Effect of Polyalthia suberosa on the hole cross test in mice (mean ± SEM, n = 6).
Group
Dose
Number of head dips
0 min
30 min
60 min
90 min
120 min
Control
10 ml kg−1
5 ± 0.70
6.2 ± 0.37
6.2 ± 0.48
6.6 ± 0.40
8.6 ± 0.24
Standard
3 mg kg−1
1.6 ± 0.51
1.2 ± 0.37
1.6 ± 0.40
1.2 ± 0.58
0.2 ± 0.20
PS-250
250 mg kg−1
0.0 ± 0.0
3.25 ± 1.65
3.75 ± 1.44
2.5 ± 1.32
2.0 ± 1.23
PS-500
500 mg kg−1
0.0 ± 0.0
0.25 ± 0.25
0.75 ± 0.48
2.25 ± 1.31
2.25 ± 1.31
indicates < 0.05, indicates < 0.01, and indicates < 0.001 when compared with control.
