Ethnopharmacological-Based Validation of Polyalthia suberosa Leaf Extract in Neurological, Hyperalgesic, and Hyperactive Gut Disorders Using Animal Models
Table 5
Effect of Polyalthia suberosa on the hole board test in mice (mean ± SEM, n = 6).
Group
Dose
Number of movements (% of movement inhibition)
0 min
30 min
60 min
90 min
120 min
Control
10 ml kg−1
22.75 ± 0.95
24.5 ± 0.65
25.75 ± 0.85
27.25 ± 0.85
30.25 ± 0.85
Standard
3 mg kg−1
15.25 ± 0.95
7.25 ± 0.63
6.25 ± 0.62
6 ± 0.82
5.75 ± 0.48
PS-250
250 mg kg−1
22.25 ± 0.48
16.25 ± 0.95
13.75 ± 1.03
10.75 ± 0.75
11.25 ± 0.75
PS-500
500 mg kg−1
21.5 ± 0.65
14.5 ± 1.05
11.5 ± 1.04
8.25 ± 0.63
8.25 ± 0.48
indicates < 0.05, indicates < 0.01, and indicates < 0.001 when compared with control.
