The Potential of Jatropha variegata Fruits as a Natural Contraceptive: Antifertility Activity and Phytochemical Analysis
Table 5
Antiestrogenic effect of the methanol extract of J. variegata fruit on body weight and % increase of ovarian weight in female rats.
Treatment group
Initial body weight (g)
Final body weight (g)
Weight of the ovary (mg/100 g body weight)
% increase in ovarian weight
Left side
Right side
Control Tween 80 (3% v/v)
223.83 ± 6.89
195.50 ± 3.85
13.44 ± 1.09
16.50 ± 1.51
22.77 ± 6.68
Estradiol valerate (0.1 mg)
202.00 ± 2.44
197.00 ± 3.51
10.75 ± 0.83
18.12 ± 0.94
71.17 ± 9.38∗∗
J. variegata (300 mg/kg)
195.80 ± 17.43
187.60 ± 9.37
13.45 ± 0.45
22.42 ± 1.22
66.86 ± 8.53∗∗
J. variegata (300 mg/kg) + estradiol valerate
200.83 ± 1.73
196.50 ± 10.15
11.18 ± 1.45
17.89 ± 1.32
53.80 ± 8.76∗
n = 6 in each group. Values are expressed as means ± SEM. < 0.05 and < 0.01 compared to the control group. Data were analyzed by one-way analysis of variance followed by Tukey’s post hoc test using SPSS software.
