Efficacy and Safety of Yangyin Shuxin Decoction—a Chinese Herbal Medicine Formula For Heart Failure with Preserved Ejection Fraction: A Randomized Controlled Trial
Table 1
Baseline demographic and clinical characteristics.
Variables
Total (n = 63)
Treatment group (n = 31)
Control group (n = 31)
Age (yrs)
69.44 ± 6.04
69.32 ± 6.18
69.56 ± 5.99
0.876
Females (n %)
50 (79.37)
25 (80.65)
25 (80.65)
0.805
SBP (mmHg)
136.63 ± 16.60
133.23 ± 14.94
139.94 ± 17.68
0.109
DBP (mmHg)
78.16 ± 10.57
75.58 ± 10.26
80.66 ± 10.43
0.056
HR (bpm)
69.78 ± 13.63
69.16 ± 14.56
70.38 ± 12.87
0.727
Past medical history
CHD (n %)
25 (39.68)
12 (38.71)
13 (40.63)
0.877
HTN (n %)
52 (82.54)
24 (77.42)
28 (87.50)
0.292
DM (n %)
16 (25.40)
7 (22.58)
9 (28.13)
0.613
Arrhythmia (n %)
29 (46.03)
14 (45.16)
15 (46.88)
0.891
HLD (n %)
30 (47.62)
14 (45.16)
16 (50.00)
0.701
NYHA functional classification
Class II (n %)
49 (77.78)
22 (70.97)
27 (84.38)
0.201
Class III (n %)
14 (22.22)
9 (29.03)
5 (15.63)
0.201
Concomitant medications
Aspirin (n %)
44 (69.84)
21 (67.74)
23 (71.88)
0.721
Beta-blockers (n %)
31 (49.21)
13 (41.94)
18 (56.25)
0.256
ACEI (n%)
2 (3.17)
2 (6.45)
0 (0.00)
0.147
ARB (n %)
28 (44.44)
12 (38.71)
16 (50.00)
0.367
CCB (n %)
31 (49.21)
13 (41.94)
18 (56.25)
0.256
Nitrate (n%)
16 (25.40)
5 (16.13)
11 (33.33)
0.096
Statin (n %)
35 (55.56)
15 (48.39)
20 (62.50)
0.260
MRA (n %)
6 (9.52)
4 (12.90)
2 (6.25)
0.372
Non‐MRA diuretics (n %)
13 (20.63)
6 (19.35)
7 (21.88)
0.805
Data are expressed by mean ± SD, median (interquartile range) or number (%) of patients.
