BXD was superior to WM alone in the treatment of GERD, but there was no significant difference in gastroscopy results or on the occurrence of adverse reactions.
BXD was superior than conventional WM to treat GERD without inducing severe adverse reactions.
①: Consensus Opinion on GERD in China [25]; ②: Chinese Herbal Medicine New Medicine ClinicalResearch Guiding Principle [26]. BXD : Banxia Xiexin decoction; NERD: nonerosive reflux disease; RE: reflux esophagitis; WM : Western medicine; NA: not applicable.