Research Article

Treatment of the Gastroesophageal Reflux Disease with Chinese Herbal Medicine (BanxiaXiexin Decoction): Evidence from Meta-Analysis

Table 4

Results of evidence quality.

StudiesOutcomesLimitationsInconsistencyIndirectnessImprecisionPublicationbiasRelative effect(95% CI)Quality

Yu [19]Recovery rate−10000RR 1.55 (1.17, 2.05)M
Effective rate−10000RR 1.15 (1.10,1.21)M
Efficacy under gastroscope−10000RR 1.21 (1.09, 1.35)M

Chen [20]Recurrence rate−100−10RR 0.25 (0.09, 0.72)L
Effective rate−10000OR 3.96 (2.96, 5.28)M
Efficacy under gastroscope−100−10OR 1.99 (0.99, 3.65)L
Adverse events−1−100−1OR 0.26 (0.06, 1.07)CL

Dai [21]Effective rate−1000−1OR 3.25 (2.15, 4.94)L
Efficacy under gastroscope−1−1000OR 1.96 (1.21, 3.18)L
Acid regurgitation−1−1000SMD 0.51 (-0.90, 1.92)L
Heartburn−1−1000SMD -0.68 (-1.25, -0.12)L
Recurrence rate−1−10−10OR 0.35 (0.11, 1.16)CL

Zheng [22], 2016Effective rate−1−1000OR 4.16 (2.91,5.59)L
Recurrence rate−1−1000OR O.27 (0.15,0.48)L

Qi[23], 2016Effective rate−1−100−1OR 3.31 (2.57,4.27)CL
Recovery rate−1−10−1−1OR 1.88 (1.53, 2.31)CL

Guo[24], 2015Effective rate−1000−1OR 3.41 (2.22, 5.23)L
Efficacy under gastroscope−100−1−1OR 1.58 (1.04, 2.41)CL
Recurrence rate−1000−1OR 0.23 (0.14,0.40)L

-1: downgrade; 0: not downgrade; CL: critically low; L : Low; M: moderate; RR: relative risk; OR: odds ratio; SMD : SMD: standardized mean difference.