Metabolomics Deciphering the Potential Biomarkers of Hengqing I Prescription against Vascular Dementia

Table 2

Differential analysis of the metabolites in VaD and normal groups (as shown in the first 20 lines).

Name	m/z^1	RT^2 (min)	VIP	-value	LogFC^3
Biotin	245.09	5.12	1.05	1.52E-06	4.10
N-Acetyl-L-leucine	174.11	4.15	1.48	8.72E-10	3.72
cis-4-Hydroxy-D-proline	132.06	11.87	1.87	2.75E-10	2.68
4-Hydroxy-6-methyl-2-pyrone	127.04	3.15	1.60	1.21E-09	2.46
1,7-Dimethyluric acid	197.07	6.10	1.13	1.56E-04	2.33
H-Pro-Hyp-OH	229.12	11.92	1.97	1.47E-09	2.29
Decanoylcarnitine	316.25	6.53	1.79	2.44E-14	2.21
5-Methyluridine	259.09	11.17	1.60	5.52E-04	2.18
5-Aminolevulinic acid	132.06	5.00	1.08	6.75E-05	2.04
Naringenin	273.08	6.45	1.06	9.81E-03	-2.00
3-Aminoisobutyric acid	104.07	10.51	1.34	7.05E-06	1.86
Kynurenine	209.09	8.96	1.87	3.67E-10	1.82
Isoleucine	132.10	9.21	2.33	4.17E-09	1.81
6-Hydroxynicotinic acid	140.04	8.97	1.31	9.53E-04	1.80
Sorbitol	205.07	9.84	1.44	2.73E-02	-1.79
Deoxycarnitine	146.12	10.29	1.73	3.59E-07	1.77
Asp-Phe	281.10	10.84	1.74	1.09E-03	1.69
Tyrosine	182.08	10.09	1.70	3.80E-03	-1.66
Methionine	150.06	9.55	1.88	8.48E-09	1.54
Trigonelline	160.04	9.83	1.98	1.67E-05	-1.48

¹Mass-to-charge ratio; ²retention time; ³logarithm of fold change based on two.