Metabolomics Deciphering the Potential Biomarkers of Hengqing I Prescription against Vascular Dementia

Table 3

Differential analysis of the metabolites in KDBS and non-KDBS groups (as shown in the first 20 lines).

Name	m/z^1	RT^2 (min)	VIP	-value	LogFC^3
Pantothenic acid	220.12	5.22	1.81	3.00E − 05	5.90
Norleucine	132.10	4.15	1.80	5.55E − 09	4.66
Biotin	245.09	5.12	1.77	8.15E − 07	4.44
N-Cinnamoylglycine	206.08	4.64	1.64	9.54E − 05	4.15
Pyroglutamic acid	130.05	6.29	1.50	4.77E − 08	3.61
N-Acetyl-L-leucine	174.11	4.15	1.90	5.87E − 10	3.47
5-Aminolevulinic acid	132.06	5.00	1.45	6.06E − 07	2.59
Hexamethylene bisacetamide	201.16	8.88	1.20	1.64E − 03	1.90
cis-4-Hydroxy-D-proline	132.06	11.87	1.90	1.10E − 07	1.88
N-Acetylputrescine	131.11	9.54	1.70	4.75E − 09	−1.83
3-Indoleacetic acid	176.07	6.68	1.88	2.94E − 04	−1.81
H-Pro-Hyp-OH	229.12	11.92	1.73	3.73E − 07	1.75
Phosphocholine	184.07	12.71	1.39	1.12E − 02	1.50
S-Adenosyl-L-homocysteine	385.13	12.16	2.02	1.92E − 05	1.49
5-Methylcytidine	258.11	8.56	1.08	3.83E − 04	1.48
D-Maltose	343.12	12.34	1.59	2.91E − 03	1.44
Acetylhomoserine	162.07	7.21	1.60	1.60E − 06	−1.42
Ecgonine	186.11	4.31	1.46	2.62E − 03	−1.35
Hippuric acid	180.07	4.44	1.76	2.45E − 06	−1.35
L-Citrulline	176.10	12.21	1.75	3.93E − 03	1.32

¹Mass-to-charge ratio; ²retention time; ³logarithm of fold change based on two.