Metabolomics Deciphering the Potential Biomarkers of Hengqing I Prescription against Vascular Dementia

Table 4

Differential analysis of the metabolites in HQI and control groups (as shown in the first 20 lines).

Name	m/z^1	RT^2 (min)	VIP	-value	LogFC^3
Histamine	1act12.09	9.14	1.55	8.58E − 03	−3.11
Hexamethylene bisacetamide	201.16	8.88	2.43	2.48E − 06	−3.03
Dopamine	154.10	9.15	1.21	8.12E − 03	−2.84
Decanoylcarnitine	316.25	6.53	2.20	2.04E − 07	2.54
Xanthurenic acid	206.04	7.44	1.96	2.17E − 04	−2.44
N-Acetyl-L-leucine	174.11	4.15	1.77	6.18E − 03	2.42
4-Methylpyrimidine	95.06	9.14	1.42	9.51E − 03	−2.36
1-Methylnicotinamide	137.07	9.37	2.16	2.67E − 09	−2.08
5-Methyluridine	259.09	11.17	1.64	1.73E − 02	2.06
Kynurenine	209.09	8.96	2.14	2.03E − 06	2.04
H-Pro-Hyp-OH	229.12	11.92	1.78	1.24E − 05	1.83
Methionine	150.06	9.55	2.24	3.08E − 06	1.82
Methylguanidine	74.07	8.80	1.30	3.91E − 03	1.76
Isoleucine	132.10	9.21	2.33	1.33E − 10	1.72
5-Methylcytosine	126.07	8.26	1.42	1.10E − 04	1.63
Asp-Phe	281.10	10.84	1.86	7.88E − 03	1.56
Propionylcarnitine	218.14	8.81	1.48	2.53E − 03	1.54
Tyrosine	182.08	10.09	1.68	3.20E − 02	−1.53
Kaempferol	287.05	1.52	1.07	3.42E − 02	1.46
Histidine	156.08	13.74	1.52	3.11E − 04	1.24

¹Mass-to-charge ratio; ²retention time; ³logarithm of fold change based on two.